Rsad2 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comRsad2 Polyclonal Antibody for Mouse(Mus musculus)

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Rsad2 (Gene name),

Radical S-adenosyl methionine domain-containing protein 2 (Protein name ), RSAD2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Rsad2(Vig1);

Protein name:

Radical S-adenosyl methionine domain-containing protein 2;

Alternative:

Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible;Viperin;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with FPPS.

Function:

Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Inhibits replication of Sindbis virus.

Subcellular Location:

Endoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side Probably associates with the cytosolic side of the endoplasmic reticulum.

Protein Attributes:

Sequence length:

362

Sequence:

50:

100:

150:

200:

250:

300:

350:

362:

YVWSKADLKL | DW

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q8CBB9

UniGene:

Mm.24045

KEGG:

mmu:58185

SMR:

Q8CBB9

Pfam:

PF04055

Uniprot:

Q8CBB9

FOR

ELISA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2

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E3787h

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96T

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ELISA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2

Cat.:

E3787m

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96T

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ELISA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2

Cat.:

E3787r

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96T

ELISA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2

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E3787b

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96T

ELISA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2

Cat.:

E3787p

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96T

CLIA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2

Cat.:

U3787r

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Packing:

96T

CLIA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2

Cat.:

U3787m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2

Cat.:

U3787h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2

Cat.:

U3787b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2

Cat.:

U3787p

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96T

Polyclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2

Cat.:

P3787Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2

Cat.:

P3787Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2

Monoclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2

Protein for Mouse Radical S-adenosyl methionine domain-containing protein 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Vesicular stomatitis virus and pseudorabies virus induce a vig1/cig5 homologue in mouse dendritic cells via different pathways."
Boudinot P. , Riffault S. , Salhi S. , Carrat C. , Sedlik C. , Mahmoudi N. , Charley B. , Benmansour A.
J. Gen. Virol.81:2675-2682(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INDUCTION
strain: C57BL/6.
tissue: Lymph node.
2.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Bone.
tissue: Bone marrow.
3.

"Cloning of mouse full open reading frames in Gateway(R) system entry vector (pDONR201)."
Ebert L. , Muenstermann E. , Schatten R. , Henze S. , Bohn E. , Mollenhauer J. , Wiemann S. , Schick M. , Korn B.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: NMRI.
tissue: Mammary tumor.
5.

"Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus."
Chin K.-C. , Cresswell P.
Proc. Natl. Acad. Sci. U.S.A.98:15125-15130(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3-362
6.

"The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents."
Olofsson P.S. , Jatta K. , Waagsaeter D. , Gredmark S. , Hedin U. , Paulsson-Berne G. , Soederberg-Naucler C. , Hansson G.K. , Sirsjoe A.
Arterioscler. Thromb. Vasc. Biol.25:E113-E116(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
7.

"Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1."
Severa M. , Coccia E.M. , Fitzgerald K.A.
J. Biol. Chem.281:26188-26195(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
8.

"Identification and characterization of interferon-induced proteins that inhibit alphavirus replication."
Zhang Y. , Burke C.W. , Ryman K.D. , Klimstra W.B.
J. Virol.81:11246-11255(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"Viperin is required for optimal Th2 responses and T-cell receptor-mediated activation of NF-kappaB and AP-1."
Qiu L.Q. , Cresswell P. , Chin K.C.
Blood113:3520-3529(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
10.

"The antiviral protein, viperin, localizes to lipid droplets via its N-terminal amphipathic alpha-helix."
Hinson E.R. , Cresswell P.
Proc. Natl. Acad. Sci. U.S.A.106:20452-20457(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
11.

"Viperin: a multifunctional, interferon-inducible protein that regulates virus replication."
Seo J.Y. , Yaneva R. , Cresswell P.
Cell Host Microbe10:534-539(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
12.

"Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells."
Saitoh T. , Satoh T. , Yamamoto N. , Uematsu S. , Takeuchi O. , Kawai T. , Akira S.
Immunity34:352-363(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH IRAK1 AND TRAF6
13.

"The interferon-inducible gene viperin restricts West Nile virus pathogenesis."
Szretter K.J. , Brien J.D. , Thackray L.B. , Virgin H.W. , Cresswell P. , Diamond M.S.
J. Virol.85:11557-11566(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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